Microsoft Exchange Servers security updates have been released for March 2022.
These updates are available for the following specific builds of the Exchange Server:
Exchange Server 2013 CU23
Exchange Server 2016 CU21 and CU22
Exchange Server 2019 CU10 and CU11
The recommendation is to install these updates immediately to protect your environment.
You can installation security patches if you are in the specified Cumulative Update(CU) versions.
If you aren’t in the specified cumulative updates, you must first installation cumulative updates.
Note : Don't double-click the 'MSP file' to run it. Run Command Prompt (not powershell) as an Administrator.
Further Information and Guidance
Exchange Team Blog
Exchange Updates Step-by-Step Guide
Determine Which Updates are Needed
Security Update Guide
Have a nice day !