Microsoft Exchange Servers security updates have been released for March 2022.
These updates are available for the following specific builds of the Exchange Server:
The recommendation is to install these updates immediately to protect your environment.
You can installation security patches if you are in the specified Cumulative Update(CU) versions.
If you aren’t in the specified cumulative updates, you must first installation cumulative updates.
Don't double-click the 'MSP file' to run it. Run Command Prompt (not powershell) as an Administrator.
Have a nice day !